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EDJ-Egyptian Dental Journal. 1993; 39 (3): 491-494
in English | IMEMR | ID: emr-27618

ABSTRACT

45 male albino rats were used to study the effect of deep submucosal implantation of DMBA on lingual carcinogenesis. The results showed development of different mesenchymal neoplasm [fibroma, fibrosarcoma and leiomyosarcoma]. So, this method of implantation could not be used as an ideal animal model for production of single known neoplasm as had been investigated by many investigators before


Subject(s)
Animals, Laboratory , Tongue Neoplasms/chemically induced , Mesoderm/drug effects , Rats , Fibroma/chemically induced , Fibrosarcoma/chemically induced , Leiomyosarcoma/chemically induced
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